40多歲成人的代謝症候群與16歲時看電視及運動習慣有關


  【24drs.com】根據這項主題首次發表的一篇前瞻研究,16歲時看電視和休閒運動的習慣可預測43歲時的代謝症候群。
  
  瑞典Umea大學Patrik Wennberg博士等人在1月22日糖尿病照護期刊線上發表該篇文獻,對於看電視和後續代謝風險,這篇研究支持之前的研究結果,且提供了新證據指出,這個關聯在生命週期的影響期間相當長:從青春期到中年。
  
  研究者也相信,有不同的機轉影響看電視和運動習慣的關聯,因為這些活動和不同的代謝症候群因素有關。
  
  然而,他們指出,這些結果認為,青少年時少看電視、加上規律運動,或許可促成長大後的心臟代謝健康。
  
  針對北瑞典以人口為基礎的一個世代、採用自我評估問卷評估16歲時看電視和休閒運動的習慣。依據國際糖尿病聯合會(IDF)規範,有888個參與者(原始樣本數的82%)在43歲時確認有代謝症候群,定義是女性腰圍大於等於80公分,男性大於等於94公分,且下列準則有兩項以上:
  * 三酸甘油脂增加(1.7 mmol/L或以上)或有接受脂質異常之治療。
  * 高密度脂蛋白(HDL)膽固醇降低(小於1.29 mmol/L(女性)或小於1.03 mmol/L(男性))或有接受脂質異常之治療。
  * 血壓上升(收縮壓130 mm Hg或以上、舒張壓85 mm Hg或以上)或有進行高血壓治療。
  * 空腹血糖值上升(5.6 mmol/L或以上)或有第2型糖尿病診斷。
  
  26.9%的參與者被發現有代謝症候群;表示在16歲時一天看多部電視節目者,在43歲時患有代謝症候群的比率,是每週看一個節目或更少者的2倍之多(校正勝算比[OR],2.14);同樣地,表示每月只有數次休閒運動者,比那些在青少年時期每天都有休閒運動者更可能在成年時患有代謝症候群(OR,2.31)。
  
  Wennberg博士等人的結果認為,看電視和休閒運動與後續的心臟代謝風險都有所謂劑量反應的關聯。
  
  16歲時的看電視習慣與43歲時的腹部肥胖、HDL膽固醇低、高血壓有關。青少年時的休閒運動少者,與成年時腹部肥胖及三酸甘油脂上升有關。作者們表示,這些觀察發現認為,看電視/久坐和運動與後續之代謝風險的關聯,可藉由不同的心臟代謝路徑調控。
  
  他們指出,這意味著需針對久坐行為,如看電視、或增加休閒運動等進行不同的介入策略。
  
  作者們結論指出,青少年時少看電視、青少年和成年時都要有規律的休閒運動,可促成後來的心臟代謝健康。
  
  資料來源:http://www.24drs.com/professional/list/content.asp?x_idno=6980&x_classno=0&x_chkdelpoint=Y
  

Metabolic Syndrome in 40s Linked to TV, Exercise at Age 16

By Lisa Nainggolan
Medscape Medical News

Television viewing habits and leisure-time physical activity at the age of 16 years independently predicts the metabolic syndrome at age 43, according to the first prospective study to examine this.

The work "supports previous findings" and, for TV viewing and subsequent metabolic risk, "provides new evidence that this association may stretch over a considerable proportion of the lifespan: from adolescence to mid-adulthood," say Patrik Wennberg, PhD, from Umea University, Sweden, and colleagues in their article published online January 22 in Diabetes Care.

The researchers also believe that separate mechanisms may be at play here for TV-viewing and physical-activity habits, because these activities were linked to different metabolic-syndrome components.

Nevertheless, the findings "suggest that reduced TV viewing in adolescence, in addition to regular physical activity, may contribute to cardiometabolic health later in life," they state.

More TV, Less Exercise Doubled Metabolic Syndrome

TV viewing habits and leisure-time physical activity at age 16 years were assessed by self-administered questionnaires in a population-based cohort in Northern Sweden. The presence of the metabolic syndrome at age 43 years was ascertained in 888 participants (82% of the baseline sample) using the International Diabetes Federation (IDF) criteria, defined as a waist circumference 80 cm or greater for women and 94 cm or greater for men and 2 or more of the following criteria:

  • Increased triglycerides (1.7 mmol/L or greater) or specific treatment for that lipid abnormality.

  • Reduced high-density lipoprotein (HDL) cholesterol (less than 1.29 mmol/L for women and less than 1.03 mmol/L for men) or specific treatment for that lipid abnormality.

  • Increased blood pressure (systolic BP 130 mm Hg or greater or diastolic 85 mm Hg or greater) or treatment of hypertension.

  • Increased fasting glucose (5.6 mmol/L or greater) or diagnosed type 2 diabetes.

Metabolic syndrome was identified in 26.9% of participants. Those who reported "watching several [TV] shows a day" at 16 were twice as likely to have the metabolic syndrome at age 43 than those who said they watched "1 show/week" or less (adjusted odds ratio [OR], 2.14). Similarly, those who noted leisure-time physical activity "several times per month" were more likely to have metabolic syndrome later in life than those who reported "daily" leisure-time physical activity in their teens (OR, 2.31).

"Our results suggest a dose-response relationship for both TV viewing and leisure-time physical activity with subsequent cardiometabolic risk," write Dr. Wennberg and colleagues.

TV viewing at age 16 years was linked to central obesity, low HDL cholesterol, and hypertension at age 43 years. Low leisure-time physical activity in the teen years was associated with central obesity and raised triglycerides later in life. These observations suggest that associations between TV viewing/sedentary behavior and physical activity with subsequent metabolic risk may be mediated via different cardiometabolic pathways, the authors say.

This possibility means that "different strategies may need to be adopted" with regard to interventions targeting sedentary behavior, such as TV viewing, and those aiming to increase leisure-time physical activity, they note.

"Reduced TV viewing in adolescence, in addition to and independently of regular leisure-time physical activity in adolescence and adulthood, may contribute to cardiometabolic health later in life," the authors conclude.

The authors have disclosed no relevant financial relationships.

Diabetes Care. Published online January 22, 2013.

    
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