含有牛奶的飲食配方可能導致罹患第一型糖尿病機率升高

更多的證據支持改以母乳餵食高危險群嬰兒

  雖然,關於爭論「以牛奶餵食嬰孩是否會升高罹患第一型糖尿病的機率」持續進行;然而,最近新的證據支持前者的說法,肯定的確會昇高罹病的機率。在一份以罹患第一型糖尿病高危險群的嬰孩為對象的研究中,發現那些在飲食配方中含有牛奶的嬰孩較含有酪蛋白水解物的嬰孩,具有較高的罹病機率。這些發現都在最近費城召開的美國糖尿病協會發表。

 
 

Cow's Milk Formula May Increase Type 1 Diabetes Risk

More Evidence to Support Breastfeeding At-Risk Infants

By Denise Mann
WebMD Medical News

Reviewed by Aman Shah, MD

July 23, 2001 -- Debate continues about whether feeding cow's milk to an infant increases the risk of developing type 1 diabetes -- but new evidence supports that it in fact does. In a study of newborns at high risk for type 1 diabetes, those fed infant formula made with cow's milk had a higher risk of developing the disease compared with those fed formula containing casein hydrolysates. The findings were reported recently at the annual meeting of the American Diabetes Association in Philadelphia.

"The studies [to date] are a mixed bag," says Alan Greene, MD, assistant clinical professor of pediatrics at Stanford University School of Medicine in Palo Alto, Calif. "Clearly the answer is not in, but if there is someone with type 1 in the immediate family, I recommend breastfeeding for as long as possible -- at least 1 year -- or to avoid cow's milk formula for the first 6 to 8 months."

After exclusive breastfeeding, 208 babies who carried alleles putting them at high risk of developing type 1 diabetes were randomized to receive formula made with or without cow's milk until they were 6-8 months of age. During the 3-year observation period, the researchers documented a 39-57% decrease in auto-antibodies and antibodies to islet cells suggestive of type 1 diabetes in infants on casein hydrolysate compared with infants on the cow's milk-based formula.

Overall, those fed formula made without cow's milk were about 50% less likely to develop type 1 diabetes. Thus the researchers postulate that it may be possible to change autoimmunity patterns through dietary interventions.

Another study has shown that drinking about three glasses of cow's milk per day increased the risk type 1 diabetes among children with siblings who have the disease, suggesting that some proteins in cow's milk may induce the immune system to attack insulin-producing cells.

Other studies have, however, have found that infants fed cow's milk are no more likely to develop the disease than infants who are breastfed. Experts say that a new 17-country trial of about 3,000 children may provide a definitive answer.

"The studies are split," says John Buse, MD, the director of the Diabetes Care Center at the University of North Carolina at Chapel Hill. "I think breastfeeding is good, and it may also be good for reducing diabetes risk."

"The most recent literature supports that breastfeeding can prevent type 1 diabetes," agrees Davida Kruger, RN, diabetes educator and nurse practitioner at Henry Ford Hospital in Detroit.

 

© 2001 WebMD Corporation. All rights reserved.

 

    
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