飲用瑪黛茶與骨密度較高有關


【24drs.com】2012年1月的Bone期刊中,阿根廷骨質疏鬆預防與治療計畫的Andrea Conforti醫師等人報告指出,停經後婦女飲用瑪黛茶(Ilex paraguariensis)者,和沒有喝該種飲品者相比,骨密度(BMD)值較高。
  
  瑪黛茶是風行於南美洲、一種含有黃嘌呤的飲料,它可製為茶葉以熱水沖泡後過濾飲用。更普遍的是,將茶葉放在一個乾葫蘆中、以熱水反覆沖泡、用一個金屬吸管飲用,本研究的研究對象即使用此方法。這種飲用方法,所含的咖啡因含量可達約330 mg/L。
  
  這篇跨世代觀察型研究中,研究者探討了該骨質疏鬆計畫中,每天飲用瑪黛茶至少1 L、至少5年的停經後婦女(n = 146人),並根據年紀及停經時間與沒有喝這種茶飲的婦女配對。兩組都屬於久坐類型,定義為沒有進行運動計畫。
  
  兩組在年紀、停經後時間、身高、體重、熱量攝取都進行配對,不過,喝茶組的身體質量指數比沒有喝茶組多1.1 kg/m2。
  
  目前有抽菸或者以前曾抽菸者、每週喝酒超過50 g的婦女、目前有接受荷爾蒙替代治療者、接受雙磷酸鹽類治療超過6個月者、接受長期皮質類固醇治療者都被排除。
  
  由不知道每個研究對象飲用瑪黛茶狀態的研究者分析所有BMD測量參數。
  
  使用雙能量X光吸收儀(DXA)測量BMD,研究者發現,喝茶者的腰椎BMD比沒有喝茶者多9.7%(分別是0.952 g/cm2和0.858 g/cm2;P < .0001),股骨頸的BMD則是多6.2%(分別是0.817 g/cm2和0.776 g/cm2;P = .0002)。研究者進行多重回歸分析後發現,除了身體質量指數,在這些地區,飲用瑪黛茶是唯一與BMD顯著相關的變項(P = .0028)。
  
  與對照組相比,雖然各年齡層的瑪黛茶組有比較高的腰椎和股骨頸BMD,兩組的BMD-年紀回歸線斜率並無差異,表示喝茶者和對照組隨時間流失的BMD相似。
  
  進行DXA掃描時,兩組的低影響骨折數相似(喝茶組13例、對照組17例;P = .5637)。
  
  作者們結論表示,長期飲用瑪黛茶與腰椎及股骨頸BMD較高有關,認為這種茶飲對停經後婦女的骨密度有正面幫助,他們也指出,根據其他研究者以前所提「咖啡因對BMD有害的報告」、有關飲用瑪黛茶的假設應被排除。
  
  研究限制是,回溯設計的本質、研究對象自我報告飲用瑪黛茶的情況、研究對象是參與骨質疏鬆預防診斷與治療之計劃對象,研究結果無法一般化到年輕的婦女、男性或孩童。
  
  資料來源:http://www.24drs.com/professional/list/content.asp?x_idno=6703&x_classno=0&x_chkdelpoint=Y
  

Higher Bone Mineral Density Related to Drinking Yerba Mate

By Daniel M. Keller, PhD
Medscape Medical News

January 2, 2012 — Postmenopausal women who consumed yerba mate (Ilex paraguariensis) tea had higher bone mineral density (BMD) compared with women who did not drink the tea, Andrea Conforti, MD, from the Program for the Prevention and Treatment of Osteoporosis in Mendoza, Argentina, and colleagues report in the January 2012 issue of Bone.

Yerba mate is a xanthine-containing beverage that is popular in South America. It may be prepared as an infusion of dried leaves steeped in hot water and then filtered. More commonly, it is consumed through a metal straw inserted into a dried gourd containing the leaves, over which hot water is poured repeatedly, and it was these users who were included in the study. By this method, the tea contains caffeine at a concentration of about 330 mg/L.

In this cross-sectional, observational study, investigators identified postmenopausal women in the osteoporosis program who drank at least 1 L of yerba mate tea daily for at least 5 years (n = 146) and matched them by age and time since menopause with an equal number of women who did not drink yerba mate tea. Both groups were fairly sedentary, defined as not being in a program of physical exercise.

The 2 groups were well matched for age, time since menopause, height, body mass, and calcium intake. However, the tea drinkers had a body mass index 1.1 kg/m2 greater than the nondrinkers.

Current or former cigarette smokers, women who consumed more than 50 g of alcohol per week, those currently receiving hormone replacement therapy, those who had received bisphosphonate treatment for more than 6 months, or those who received chronic corticosteroid treatment were excluded.

One of the investigators, who was blinded to the yerba mate drinking status of each participant, performed the analysis of all the BMD measurements.

Measuring BMD by dual-energy X-ray absorptiometry (DXA), the researchers found that the tea drinkers had 9.7% greater lumbar spine BMD compared with non–tea drinkers (0.952 g/cm2 vs 0.858 g/cm2, respectively; P < .0001), as well as 6.2% greater femoral neck BMD (0.817 g/cm2 vs 0.776 g/cm2, respectively; P = .0002). By a multiple regression analysis, the researchers found that in addition to body mass index, drinking yerba mate tea was the only variable that significantly correlated with BMD at these sites (P = .0028).

Although the yerba mate group had higher lumbar spine and femoral neck BMD at all ages compared with control patients, the slopes of the regression lines for BMD vs age did not differ between the groups, indicating that loss of BMD over time was similar for the tea-drinkers and the control participants.

At the time of DXA scanning, the number of low-impact bone fractures was similar between the groups (13 for tea drinkers and 17 for control patients; P = .5637).

The authors conclude that chronic consumption of yerba mate tea was associated with greater BMD at the lumbar spine and femoral neck, "suggesting a protective effect of this tea on bone mass of postmenopausal women." They also note that their earlier hypothesis that yerba mate consumption, based on other investigators' reports of a deleterious effect of caffeine on BMD, "should be rejected."

Limitations of the study are its retrospective nature, participants' self-reports of yerba mate consumption, and that the study participants were a selected population of postmenopausal women in a program for the prevention, diagnosis, and treatment of osteoporosis. Results may not be generalizable to younger women, men, or children.

The study was supported by Obra Social de Empleados Publicos, Mendoza, Argentina. The authors have disclosed no relevant financial relationships.

Bone. 2012;50:9-13.

    
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